منابع مشابه
Fighting infections
Fighting disease: In the first �eca�es after the intr��ucti�n �f antibi�tics,� there �as �i�es�rea� ��timism that the fi�ht a�ainst infecti�us �isease c�ul� be ��n. This early a�vert f�r �enicillin �as tar�ete� at W�rl� War II servicemen. (Picture: Wiki�e�ia.) F�r a fe� �eca�es,� ar�un� the mi��le �f the 20th century,� there �as �i�es�rea� ��timism that science c�ul� �in the fi�ht a�ainst infec...
متن کاملFighting bacterial infections-future treatment options.
This review summarizes ongoing research aimed at finding novel drugs as alternatives to traditional antibiotics. Anti-virulence approaches, phage therapy and therapeutic antibodies are strategies that may yield drugs with high specificity and narrow spectra. Several candidates are currently being evaluated in clinical trials, mostly for topical applications, but so far, none have been approved ...
متن کاملFighting poverty, fighting AIDS.
J effrey sachs is an economist, not an evangelist. But give the man 10 minutes behind a microphone, and a scholarly symposium starts to feel like a revival meeting. “Ladies and gentlemen,” he tells a hushed hall after describing how AIDS sufferers die in Malawi for want of $1-a-day drugs, “this plague is exploding. Its consequences will make the world quake. Rich countries could stop the devast...
متن کاملFighting resistance.
A pioneer in the early identification of drug resistance in tuberculosis patients, Sir John Crofton and his colleagues' seminal research into multidrug therapy for tuberculosis patients in the 1950s laid the groundwork for the WHO-recommended tuberculosis treatment today. This is one of the last interviews he gave before he passed away on 3 November at the age of 97, after a career that spanned...
متن کاملFighting the Monster: Applying the Host Damage Framework to Human Central Nervous System Infections
The host damage-response framework states that microbial pathogenesis is a product of microbial virulence factors and collateral damage from host immune responses. Immune-mediated host damage is particularly important within the size-restricted central nervous system (CNS), where immune responses may exacerbate cerebral edema and neurological damage, leading to coma and death. In this review, w...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2012
ISSN: 0960-9822
DOI: 10.1016/j.cub.2012.02.028